Corticotropin-Releasing Factor Receptors and Their Interacting Proteins: Functional Consequences.
نویسندگان
چکیده
The corticotropin-releasing factor (CRF) system, which is involved in stress, addiction, and anxiety disorders such as depression, acts through G-protein-coupled receptors (GPCRs) known as type-1 and type-2 CRF receptors. The purpose of this review is to highlight recent advances in the interactions of CRF receptors with other GPCRs and non-GPCR proteins and their associated functional consequences. A better understanding of these interactions may generate new pharmacological alternatives for the treatment of addiction and stress-related disorders.
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ورودعنوان ژورنال:
- Molecular pharmacology
دوره 90 5 شماره
صفحات -
تاریخ انتشار 2016